World War I is over. Alafair Tucker is overjoyed that her elder son, George Washington Tucker, has finally returned home from the battlefields of France. Yet she is the only one in the family who senses that he has somehow changed. One rainy day, Gee Dub spies a woman trudging along the country road. Once made comfortable at the Tucker farm, Holly Johnson reveals she has forged her way from Maine to Oklahoma in hopes of finding the soldier she married before he shipped to France. At the war's end, Daniel Johnson disappeared without a trace. But when he finally turns up, shot dead, Gee Dub is arrested on suspicion of murder, and the entire extended Tucker family rallies to his defense.

Alafair Tucker’s daughter, Alice, and son-in-law, Walter Kelley, have both come down with the flu, and Alafair has moved into town to care for them. One autumn afternoon, Alice’s neighbor, Nola Thomason, and her son Lewis suddenly and unexpectedly succumb. Yet there is something about the way the pair died that causes Alafair to suspect their deaths were due to poison rather than to influenza. The epidemic is so overwhelming that it is many days before the only doctor left in town can confirm Alafair’s suspicions. The only witness to their deaths, 12-year-old Dorothy Thomason, a special friend of Alafair’s daughter, Sophronia, is so traumatized that she is rendered mute. Were Nola and her son murdered? If so, why?