With her husband Bernard two years in the grave, 79 year-old Harriet Chance sets sail on an ill-conceived Alaskan cruise only to discover that she’s been living the past 60 years of her life under entirely false pretenses. There, amid the buffets and lounge singers, between the imagined appearance of her late husband and the very real arrival of her estranged daughter, Harriet is forced to take a long look back, confronting the truth about pivotal events that changed the course of her life.
Having lost virtually everything, Benjamin Benjamin enrolls in a night class called The Fundamentals of Caregiving. He is assigned to 19-year-old Trevor, who is in the advanced stages of Duchenne muscular dystrophy. As the two embark on a wild road trip across the American West, a new camaraderie replaces the traditional boundary between patient and caregiver.