Thirty-one years after workers first broke ground, the magnificent Hotel Neversink in the Catskills finally opens to the public. Then a young boy disappears. This mysterious vanishing --- and the ones that follow --- will brand the lives of three generations. At the root of it all is Asher Sikorsky, the ambitious and ruthless patriarch whose purchase of the hotel in 1931 set a haunting legacy into motion. His daughter Jeanie sees the Hotel Neversink into its most lucrative era, but also its darkest. Decades later, Asher's grandchildren grapple with the family’s heritage in their own ways: Len fights to keep the failing, dilapidated hotel alive, and Alice sets out to finally uncover the murderer’s identity.