Talulla Demetriou, a werewolf, is grieving for her werewolf lover, Jake, whose violent death has left her alone with her own monstrousness. One the run, pursued by hunters, she must find a place to give brith to Jake's child in secret. The birth gives her some relief, thinking that the worst is over, but the worst has only just begun. She is now stuck in a race against time to save herself and her child from the hunters of the world Organisation for the Control of Occult Phenomena, blood-drinking religious fanatics, and the oldest living vampire.

Jake Marlowe is the last werewolf. Although physically healthy, he has slipped into a deep existential crisis, considering taking his own life and ending a legend that has lived for thousands of years. But there are two dangerous groups with reasons of their own for wanting Jake very much alive.